A Kinase Anchor Protein 4 Is Vulnerable to Oxidative Adduction in Male Germ Cells
Oxidative stress is a leading causative agent in the defective sperm function associated with male infertility.Such stress commonly manifests via the accumulation of pathological levels of the electrophilic aldehyde, 4-hydroxynonenal (4HNE), generated as a result of lipid peroxidation.This highly reactive lipid aldehyde elicits a spectrum of cytoto